The goal of this study is to assess the Long-term Outcomes of Critical Illness Survivors,including physical, psychological, and cognitive sequelae.
An increasing number of patients survive critical illness; however, the evidence reveals that over the same period the number of patients being sent to rehabilitation settings have tripled . For those who do survive, the latest data indicate that 50-70% of ICU "survivors" will suffer cognitive impairment and 60-80% of "survivors" will suffer functional impairment or ICU-acquired weakness (ICU-AW).Still,there is a lack valid data on the long-term impact on morbidity from prospective observational studies. Therefore, the investigators designed an observational cohort which cover a broader range of outcomes to quantify long-term physical, psychological, and cognitive impairment after intensive care unit (ICU).Intensive Care Unit patients survive from critical illness will be approached for study recruitment and participation.Survival rate,Quality of life,Cognitive impairments,Depression and anxiety,PTSD,Physical activity,Neuromuscular impairment will be assessed 3 or 6 months after ICU discharge.
Study Type
OBSERVATIONAL
Enrollment
200
Jiangyin People's Hospital
Jiangyin, Jiangsu, China
RECRUITINGZhongda Hospital
Nanjing, Jiangsu, China
NOT_YET_RECRUITINGSurvival rate of ICU survivors
Critically ill patients discharged from ICU are defined as survivors
Time frame: 3 or 6 months after ICU discharge
Assessment of life quality
Quality of Life assessed with help of The 36-item short from health survey(SF-36)questionnaire.The SF-36 has 8 scaled scores; the scores are weighted sums of the questions in each section. Scores range from 0-100. Lower scores = more disability, higher scores = less disability.The 8 sections are listed below:PF：Physical Functioning,RP：Role-Physical,BP：Bodily Pain,GH:General Health,VT：Vitality,SF：Social Functioning,RE：Role-Emotional,MH：Mental Health.
Time frame: 3 or 6 months after ICU discharge
Assessment in Physical dysfunction
Functional disabilities assessed with help of Barthel index of ADL(activities of daily living).10 variables are addressed. Range of summed total score: 0-100. higher values represent better outcome.
Time frame: 3 or 6 months after ICU discharge
Assessment in depression and anxiety
Depression and anxiety assessed with help of The Hospital Anxiety and Depression Scale(HADS).For Depression(D), 7 questions in total. Range of score for each question: 0-3. Total score summed: 0-21 ;For Anxiety(A): 7 questions in total. Range of score for each question: 0-3. Total score summed: 0-21 .For both D and A scales, higher scores represent worse outcome.
Time frame: 3 or 6 months after ICU discharge
Assessment in PTSD
Post-traumatic stress syndrome assessed with help of trauma screening questionnaire(TSQ).There are 10 questions in the TSQ. For each question, the answer is either YES or NO. More YES = worse outcome. At least 6 YES represents PTSD diagnosis.
Time frame: 3 or 6 months after ICU discharge
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Assessment in Cognitive impairments
Cognitive impairments assessed with help of mini-mental state examination(MMSE).The MMSE has 5 scaled scores; the scores are weighted sums of the questions in each section. The 5 sections and their range of score are listed below:Orientation 0-10;Registration 0-3;Attention and calculation 0-5;Recall 0-3;Language 0-9.Total score range from 0-30. Lower scores = more disability, higher scores = less disability.
Time frame: 3 or 6 months after ICU discharge
Patients' care and support needs;social and economical consequences
Patients' information of specific needs and supports and social or economical impact post ICU.
Time frame: 3 or 6 months after ICU discharge
Neuromuscular impairment
Neuromuscular impairment will be assessed by electromyography/nerve conduction study
Time frame: 3 or 6 months after ICU discharge