Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Mayo Clinic114 enrolled

Overview

This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.

Study Type

OBSERVATIONAL

Enrollment

114

Conditions

SCAD Addison Disease Ankylosing Spondylitis Antiphospholipid Antibody Syndrome Celiac Disease Crohn Disease Dermatomyositis Polymyositis Guillain-Barre Syndrome

Eligibility

Sex: ALLMin age: 18 YearsMax age: 110 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults age 18 to 110 * Residence in Olmsted County. Note: if sufficient numbers cannot be reached using only Olmsted County, will expand to the 27-county region. Exclusion Criteria: * None

Locations (1)

Mayo Clinic

Rochester, Minnesota, United States

Outcomes

Primary Outcomes

Odds of autoimmune disease in SCAD cases compared to controls

Time frame: Through study completion, or approximately 50 years (average age of study participants)

Incidence Rate of SCAD

Time frame: Through study completion, or approximately 50 years (average age of study participants)

Secondary Outcomes

SCAD recurrence

Time frame: Through study completion, or approximately 50 years (average age of study participants)

Data from ClinicalTrials.gov

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