Plasma Rich in Growth Factors in Post-extraction Sockets

Inclusion Criteria: * Upper or lower premolar or molar tooth in need of extraction and later restoration by dental implant. * Adjacent and opposing natural teeth present and healthy. * At least 3 mm from the tip of the dental root to the maxillary sinus or the inferior alveolar canal. Exclusion Criteria: * Active local infection. * Uncontrolled diabetes mellitus. * Long term (\>10 years) use of oral bisphosphonates. * Use of intravenous bisphosphonates. * Recent use (\<3 months) of antibiotics, antiinflammatories or analgesics drugs. * Pregnancy. * Smokers of more than 10 cigarettes per day. * Any oral pathology that needs to be treated before tooth extraction, particularly the presence of more than 25% of sites with bleeding on probing.