BM-MNCs and UC-MSCs Infusion for Type 2 Diabetes Mellitus Patients

Inclusion Criteria: * Who is diagnosed with Type 2 Diabetes Mellitus according to the ADA 3 years or more * Patients are able to read, write and understand ICF form and agree to participate in the study * Males and females between age 18 and 70 years at the screening. * FBG \> 7 mmol/L * 8% ≤ HbA1C ≤ 11% * Fasting C-peptide \> 0.6 ng/ml * Anti GAD (-) * The patient is treated by two oral diabetes medications but uncontrolled blood glucose (HbA1C ≥ 8%) Exclusion Criteria: * Pregnant women, planning to become pregnant and lactating women during the study period * The patient has a disease or a history of vascular disease; history of abdominal or chest aortic disease; * Patients are diagnosed with heart failure degree IV according to NYHA or kidney failure degree IV according to KDIGO; * Patients with severe malignancy or dysplasia within 5 years prior to the study period or who are suffering from severe malignant or dysplasia * Infection is undergoing antibiotic treatment or antibiotics have just been discontinued within 14 days * Hematologic disease or coagulopathy * There are abnormalities in liver function (AST and/or ALT ≥ 2 times or bilirubin ≥ 2.0 times normal value at the time of screening); * Patients with immunodeficiency diseases such as HIV or hepatitis B and C; * Acute or chronic pancreatitis or a history of acute pancreatitis; * Patients taking immunosuppressive drugs (such as azathioprine, methotrexate) within 6 months before the study time or taking immunosuppressive drugs; * The patient is unable to complete the study; * The patient is participating in another study.