White Cell Ratios as Markers of Delirium and Outcome in Acute Ischemic Stroke.

Pomeranian Medical University Szczecin1,001 enrolled

Overview

The aim of this study was to investigate the role of Neutrophil-to-Lymphocyte Ratio (NLR) and other derived white cell markers as early markers of delirium and outcome after acute ischemic stroke (AIS).

Delirium is an acute brain disorder, potentially reversible, commonly occurring in patients with acute ischemic stroke. The pathomechanism of delirium is related to neuroinflammatory process and oxidative stress. Search for readily available diagnostic marker that will aid clinicians in early identification of delirium is an on-going process. The aim of this study was to investigate the role of Neutrophil-to-Lymphocyte Ratio (NLR) and other derived white cell markers as early markers of delirium and outcome after acute ischemic stroke (AIS).

Study Type

OBSERVATIONAL

Enrollment

1,001

Conditions

Delirium Ischemic Stroke

Interventions

Delirium assessment.DIAGNOSTIC_TEST

Full blood count analysis.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age \>18 years) * acute ischemic stroke Exclusion Criteria: * hematology disorders * incomplete laboratory testing * no data regarding follow-up

Outcomes

Primary Outcomes

Early-onset-delirium.

Delirium within 24 hours from admission.

Time frame: 24 hours

Secondary Outcomes

Mortality at 30 days.

Mortality determined at follow-up on day 30 after acute ischemic stroke.

Time frame: 30 days

Mortality at 1 year.

Mortality determined at follow-up at 1 year after acute ischemic stroke.

Time frame: 1 year

Data from ClinicalTrials.gov

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