Clinical Trial for Evaluating Efficacy and Safety of PDR001 in Concurrent Plus Consolidation Versus Consolidation Only in Addition to Standard Chemoradiotherapy in Unresectable Stage III NSCLC Patients (PASTURE)

Inclusion Criteria: 1. Patients with cytologically or histologically proven, locally advanced, treatment-naïve, unresectable, both squamous and non-squamous stage III NSCLC\* (According to AJCC TNM staging 8th edition, IIIB and IIIC diseases are eligible; Inoperable stage IIIA disease without any exclusion criteria is also eligible) 2. Patients with targetable mutations such as EGFR, ALK and ROS1 are also eligible 3. Measurable disease based on RECIST 1.1 as determined by the site. 4. Men and women ≥ 20 years of age 5. A performance status of 0 - 1 on the Eastern Cooperative Oncology Group (ECOG) performance Status 6. Adequate hematologic, renal, and hepatic function as follows: * Absolute Neutrophil Count (ANC), \> 1,000/mm3 * Platelets \> 100,000/mm3 * Hemoglobin \> 9.0 g/dL * Serum creatinine \< 1.5 × upper normal limit (ULN) OR creatinine clearance \> 45 mL/min/1.73m2 * AST and/or ALT \< 2.5 × the ULN * Bilirubin \< 1.5 × the ULN 7. 12-Lead electrocardiogram (ECG) shows QTc interval ≤470 msec and without history of Torsades de Pointes or other symptomatic QTc abnormality 8. Written (signed) Informed Consent to participate in the study Exclusion Criteria: 1. Prior exposure to any anti-PD-1, anti-PD-L1, anti-PD-L2, anti-CD137, or anti-Cytotoxic T-lymphocyte-associate antigen-4 (CTLA-4) antibody 2. Active or prior autoimmune disease or history of immunodeficiency 3. Current or prior use of immunosuppressive agents within 28 days before the first dose of investigational drugs, with the exception of intranasal, inhaled, or systemic corticosteroids at physiological doses, which are not to exceed 10 mg/day of prednisone, or an equivalent corticosteroid. 4. Use of hematopoietic colony-stimulating growth factors (e.g. G-CSF, GMCSF, M-CSF), thrombopoietin mimetics or erythroid stimulating agents ≤ 2 weeks prior start of study treatment. If erythroid stimulating agents were initiated more than 2 weeks prior to the first dose of study treatment and the patient is on a stable dose, they can be maintained 5. Experience of solid organ transplant 6. Evidence of severe or uncontrolled systemic diseases, including active bleeding diatheses or active infections including hepatitis B, C and HIV. 7. Evidence of uncontrolled illness such as symptomatic congestive heart failure, uncontrolled hypertension or unstable angina pectoris. 8. Active or prior documented inflammatory bowel disease (eg, Crohn's disease, ulcerative colitis) 9. Active infection of lung, including pulmonary tuberculosis, pneumonia 10. Has a history of interstitial lung disease (ILD) or a history of pneumonitis that has required oral or IV steroids. 11. Pregnant female subject (Female subjects must have a negative urine or serum pregnancy test at screening if of childbearing potential, or be of non-child bearing potential.) 12. Lactating female subject 13. Prior malignancy, with the exception of basal cell/ squamous cell carcinoma of the skin, superficial bladder cancer, in situ cervical cancer, or has undergone potentially curative therapy with no evidence of that disease recurrence for 3 years since initiation of that therapy