Does Whole Blood Adsorber During CPB Reduce Vasoactive Drugs Postoperatively in Endocarditis Patients Undergoing Valve Surgery?

Emma Hansson20 enrolled

Overview

The study aims to investigate the effect of addition of an adsorber during cardio pulmonary bypassin patients with infective endocarditis undergoing valve surgery, and if it will decrease the use of vasoactive drugs postoperatively.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

Conditions

Infective Endocarditis

Interventions

CytoSorbDEVICE

Addition of a hemofilter to the cardiopulmonary bypass circuit

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Infected endocarditis patients undergoing heart valve surgery. 2. Age over 18 years. Exclusion Criteria: 1 Declines participation

Locations (1)

Sahlgrenska University Hospital

Gothenburg, Sweden

Outcomes

Primary Outcomes

Use of vasoactive substances

Use of norepinephrine in ICU

Time frame: 48 hours

Secondary Outcomes

Milrinone use

Amount of milrinone used 24 and 48 hours postoperatively

Time frame: 48 hours

Chest tube bleeding

Chest tube output in ml

Time frame: 48 hours

Blood transfusions

Transfusion of red blood cells, plasma and platelets

Time frame: 48 hours

Data from ClinicalTrials.gov

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