Efficacy of Kangliuwan for Recurrent Grade IV Glioma

Inclusion Criteria: 1. The patient signed "informed consent" voluntarily; 2. The age of patient is between 18 and 80 years; 3. KPS score ≥40 ; The patient has normal liver and kidney function Normal heart function Better follow-up and compliance; Exclusion Criteria: 1. The patient did not sign "informed consent" or signed unvoluntarily. 2. Non-glioma patients 3. Active infection 4. Human immunodeficiency virus (HIV) positive 5. Hepatitis C or hepatitis B infective 6. Pregnancy or breast-feeding women 7. Patients did not agree to use effective contraception during treatment and the following 3 months. 8. Patients also participated in other clinical studies. 9. The subjects researchers believe are not suitable for participation or completion of the study.