Incretin Hormone Antagonism After Bariatric Surgery

Inclusion Criteria, surgery groups: * Age \> 18 years * RYGB or SG operation \> 12 months prior to inclusion * Weight stable (± 3 kg during the last month) * HbA1c \< 48 mmol/mol before surgery, and no history of diabetes * HbA1c \< 48 mmol/mol and fasting plasma glucose \< 6.1 mmol/l at inclusion Inclusion Criteria, control group: * Age \> 18 years * no former RYGB- or SG operation * Weight stable (± 3 kg during the last month) * HbA1c \< 48 mmol/mol, fasting plasma glucose \< 6.1 mmol/l and no history of diabetes Exclusion Criteria: * Thyrotoxicosis or inadequately treated hypothyreosis * Hemoglobin \< 6.5 mmol/l at inclusion * Pregnancy or breast feeding * Medication affecting the planned examinations Matching between groups * Age * Sex * BMI at inclusion and for surgery groups also pre-surgery BMI