Macroscopic and Molecular Changes in Knee Muscular-tendon Unit in Response to Acute Resistant Load

Hillel Yaffe Medical Center300 enrolled

Overview

The aim of this study is to determine the influence of acute resistance exercises on anatomical and biological changes in the quadriceps muscle and tendons of the knee

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

300

Conditions

Quadriceps Muscle

Interventions

Acute resistant load exercisesOTHER

Leg bench and leg press acute resistant load exercises Leg-bench and leg-press acute resistant load exercises

Background QuestionnaireBEHAVIORAL

Background questionnaire will be filled out by participants

Pain QuestionnaireOTHER

Pain questionnaire regarding pain in the knee during previous 3 months

Eligibility

Sex: ALLMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Non-professional athletes * Pass heart/lung endurance tests * Pass ergometrics testing Exclusion Criteria: * Have been injured * Had physiotherapy for back or lower limbs in past 6 months * Orthopedic surgery in lower limbs

Locations (1)

Hillel Yaffe Medical Center

Hadera, Israel

Outcomes

Primary Outcomes

Genetic Changes in Knee Muscle and Tendon

Comparison of results of genetic testing both before and after interventions between the 3 groups

Time frame: One year

Ultrasound Changes in Knee Muscle and Tendon

Comparison of results of pre- and post ultrasound changes after interventions between the 3 groups

Time frame: One year

Biopsy Changes in Knee Muscle and Tendon

Comparison of changes in biopsies taken before and after interventions between the 3 groups

Time frame: One year

Central Contacts

Eias Kassem, MD

CONTACT

972-50-6246882 eiask@hy.health.gov.il

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.