Clinical Presentation and Outcomes in Patients at Risk of Type II Myocardial InfarctioN in the emerGency Department.

Hospices Civils de Lyon1,000 enrolled

Overview

Type 2 myocardial infarction has been reported in the Universal Definition of Myocardial Infarction for more than 10 years and most studies resulted in a high mortality rate. However, little to nothing is known for both criteria to define myocardial oxygenation imbalance threshold and the outcome of these patients presenting with myocardial oxygenation imbalance. The aim of this study is to compare the outcome at 6 months for patients admitted in the emergency department with a myocardial oxygenation imbalance, depending on whether a type 2 myocardial infarction occured or not.

Study Type

OBSERVATIONAL

Enrollment

1,000

Conditions

Myocardial Oxygenation Imbalance Myocardial Infarction

Interventions

Follow-upOTHER

Onset of Major Adverse Cardiovascular Event of death from all causes will be collected at 3 and 6 months after inclusion.

Medical Language ↔ Plain English

Inclusion Criteria: * age 18 years old or older ; * At least one condition of myocardial oxygenation imbalance : * Oxygen saturation below 90% ; * Haemoglobin level below 130 grams/Liter (g/L) for men, 120 g/L for women ; * Persistent heart rate over 110 beats per minute, for more than 20 minutes ; * Persistent systolic blood pressure below 90 millimeters of mercury (mmHg) for more than 20 minutes despite fluid resuscitation ; * Persistent systolic blood pressure over 180 mmHg for more than 20 minutes. Exclusion Criteria: * Patient admitted with type 1 myocardial infarction ; * Patient presenting a condition for Non Ischemic Myocardial Infarction (pulmonary embolism, acute stroke, acute kidney failure, etc…) * Patient who declines to participate; * Pregnant or breastfeeding women ; * Patient deprived of liberty (inmate, administrative protection)

Outcomes

Primary Outcomes

Onset of a Major Adverse Cardiovascular Event at 6 months

Onset of a Major Adverse Cardiovascular Event such as: * Cardiovascular death * Non fatal myocardial infarction * Admission for acute heart failure * Non fatal stroke

Time frame: 6 months