Chronic pain patients with implanted dorsal root ganglion stimulators will be randomized to receive transcranial direct current stimulation (tDCS) to the motor cortex, magneto-encephalographically (MEG) localized stimulation or sham stimulation to identify therapeutic efficacy of paired central and peripheral neuromodulation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
16
tDCS produces hyper/hypopolarizing potentials in the cortex underlying the scalp electrodes and can increase/decrease the excitability of targeted brain regions.
John Radcliffe Hospital
Oxford, Oxfordshire, United Kingdom
Change in pain scores: 21-point pain scale rating
21-point pain scale rating
Time frame: Immediately after 30 minutes of transcranial direct current stimulation
Changes in EEG recordings
Changes in electrical fields of the cortex
Time frame: Immediately after 30 minutes of transcranial direct current stimulation
Changes in Facial Expression Recognition Performance
An emotional categorisation task to identify anti-depressant effects
Time frame: Immediately after 30 minutes of transcranial direct current stimulation
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