A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of PRV-3279 in Healthy Subjects

Inclusion Criteria: 1. Healthy subjects as determined by no clinically significant deviation from normal in medical history, physical examination, ECGs, and clinical laboratory determinations. 2. Body mass index (BMI) 18 to 32 kg/m2, inclusive. 3. Male or female 18 to 50 years of age, inclusive. 4. Nonpregnant women of childbearing potential (WOCBP) and sexually active men must agree to use effective birth control with male contraception during study participation through at least 3 months after the final dose. Women of non-childbearing potential may participate. Exclusion Criteria: 1. Women who are pregnant or breastfeeding. 2. Evidence of active or chronic infections. 3. Previous exposure to PRV-3279. 4. Any reason that, in the opinion of the Investigator, would contraindicate the subject's participation in the study or confound the results of the study.