This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
60
echogenic needle will be inserted in-plane with the ultrasound beam in a posterior-to-anterior direction through the quadratus lumborum muscle until the ventral fascia of the muscle penetrated. At this point, the needle directed toward the fascial plan between the quadratus lumborum and the Psoas muscle
lumbar epidural will be performed for patients in group II using a 16-gauge Touhy epidural needle by a median approach. The T12 - L1 or L1 - L2 interspaces will be chosen for the injection. The epidural space identified by the loss of resistance technique.
South Egypt Cancer Institute
Asyut, Egypt
RECRUITINGpostoperative pain
postoperative pain intensity.
Time frame: first 24 hours postoperatively
postoperative inflammatory response
inflammatory response represented by the levels of: interleukins 1,6, and tumor necrosis factor alpha
Time frame: first 24 hours postoperatively
side effects
sedation, nausea, vomiting, and respiratory depression
Time frame: first 24 hours postoperatively
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