Objective Measurements of Lens Opacification After Intravitreal Injections

Fondation Ophtalmologique Adolphe de Rothschild

Overview

The main hypothesis is the opacification of the lens would be increase by the IVT. The opacification of the lens can be objectived by : * the objective scatter index (OSI) on the OQAS device * the average lens density (ALD) on the IOLMaster device. Eligible patients will be followed at least 12 months after in intravitreal injection and the opacification of their lens is regularly controlled with OSI and ALD. The objective is to study the dynamics of lens opacification in IVT-treated eyes evaluated by OSI for at least 1 year.

Study Type

OBSERVATIONAL

Conditions

Lens Opacification Intravitreal Injections (IVT)

Interventions

Measurement of lens opacificationDIAGNOSTIC_TEST

Measurement of OSI and ALD at inclusion and during post-IVT follow-up visits to M3, M6, and M12, +/- M18, +/- M24 and +/- M30.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria: * An indication of an intravenous injection of a dexamethasone 700 μg (Ozurdex®) or anti-VEGF for at least one of the two eyes for macular edema or neovessels linked to DMLA, retinal venous occlusion, diabetic macular edema or posterior uveitis * Phake patient, at least of the injected eye Exclusion criteria: \- Pseudophakia of the injected eye

Outcomes

Primary Outcomes

Value of the OSI (Objective Scatter Index) in one year of follow-up after IVT

Time frame: 12 months

Data from ClinicalTrials.gov

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