vitamin C or ascorbic acid has known role in tissue repair. due to it's properties(water\_soluble), vitamin c is not stored in the body and when depleted, the bleeding tendency will increase due to dysfunctional connective tissues production in vessel wall and it has some important functions in platelets.
In this randomized clinical trial, 1000 mg vitamin C will administrate intravenously a day before surgery and during surgery in patients who undergo abdominal hysterectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
80
water-soluble vitamin C injection contain of 1000 mg vitamin C that given via intravenous injection
Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences
Tehran, Iran
volume of hemorrhage
volume of hemorrhage during surgery
Time frame: During surgery
Hemoglobin value
Hemoglobin value after surgery
Time frame: 6 and 24 hours after surgery
wound healing
complications after surgery
Time frame: during 2 weeks post surgery
duration of stay in hospital
Length of stay in hospital
Time frame: up to 2 weeks post surgery
Infection
Developing infection up to 2 weeks
Time frame: up to 2 weeks post surgery
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