Video Coaching of Physical Activity in Axial Spondyloarthritis

N/AActive Not RecruitingNCT03965650

Assistance Publique - Hôpitaux de Paris60 enrolled

Overview

The primary objective of the study is to demonstrate the beneficial effect of a 3 months home-based physical exercise program supervised by online videos, in addition to the usual recommendations, in comparison with usual physical activity as recommended by the WHO. The secondary objectives of the study are : 1. to compare the following criteria between 2 groups at 3 and 6 months: * quality of life; * other measures of disease activity ; * sleep quality ; * walking ability * muscle strength of; * professional activity; * cost of cares; * evolution of weight, BMI and waist. 2. to evaluate the observance of physical activity program and its tolerance at 3 and 6 months.

The spondyloarthritides are a group of inflammatory rheumatic diseases, including ankylosing spondylitis, reactive arthritis, inflammatory bowel disease-related rheumatic disease, and psoriatic arthritis. The frequence of axial spondyloarthritis is 0.41% in the french population. This disease is associated with a reduction of physical capacities and quality of life. NSAIDs or even biologic therapies do not always permit a sufficient control of the disease. Different physical exercise programs can be effective as an additional therapy for spondyloarthritis, with positive effects on spinal mobility as well as main disease activity and functional indices (BASDAI, BASFI and BASMI). The severity of the disease does not seem to influence significantly the patients' motivation in practicing physical activity. This proposed study aims to demonstrate the beneficial effect of physical exercises coached with a specific internet program diffused on a secured platform. Each patient will have to connect 3 times weekly in order to follow the entire program. The impact will be evaluated at 3 months and 6 months. Potential impacts of video-coaching program are: * reduction of the intrinsic inflammatory activity of the rheumatic disease; * improvement of the global physical condition: muscular strength and resistance, walking ability, chest expansion; * reduction of fatigue and improvement of sleeping; * reduction of consumption of symptomatic drug (analgesics, NSAIDs, corticosteroids).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient between 18 and 65 years; * Patient can read and understand French; * Signed informed consent form to participate in the study; * Axial spondylarthritis according to ASAS criteria; * Patient with a BASDAI score between 2.5 and 5; * No change of biotherapy anti-TNF or anti-IL17 during the 3 months preceding the inclusion; * Patient equipped with an internet access; * Medical certificate of proposed physical activities. Exclusion Criteria: * All diseases (cardiovascular disease or chronic neurological disease or others) contraindicating the requested exercises according to physician; * Axial spondyloarthritis in remission defined by a BASDAI \< 2.5/10 or in excessive inflammatory activity, defined by BASDAI \> 5/10; * Pregnant woman (positive pregnant test) or woman try to conceive in following 6 months; * Patient with articular prosthesis; * Patient who already participate in a specific exercise program or practice a sport (including Yoga or Tai Chi) more than one hour per week; * Severe obesity ( BMI \> 35); * Patient without health insurance; * Patient legally unable.

Outcomes

Primary Outcomes

Proportion of patients responding to the "ASAS 20" criterion at 3 months

The primary outcome measure will be the proportion of patients simultaneously satisfying both criteria : * at least 20% improvement * improvement of at least 10 points on visual analog scale in the following domains: overall evaluation by the patient, visual analog scale (pain scale), Bath Ankylosing Spondylitis Functional Index (BASFI), and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI).

Time frame: at 3 months

Secondary Outcomes

Ankylosing Spondylitis Disease Activity : (BASDAI) (PRO)

Ankylosing Spondylitis Disease Activity will be assessed with the Bath Ankylosing Spondylitis Disease Activity (BASDAI) auto-questionnaire assessing the inflammatory activity of the disease.