Lifestyle Interventions for the Treatment of Non-alcoholic Fatty Liver Disease in Overweight and Obese Adults

Inclusion Criteria: * Man or women aged 18-65 years; * Confirmed diagnosis of NAFLD according to the 2018 Chinese Guidelines for Prevention and Treatment of NAFLD; * Body mass index (BMI)of 25.0 to 35.0 kg/m2; * Patients without medicine for treatment of NAFLD; Exclusion Criteria: * Patients with other diseases that can lead to fatty liver; * Patients use amiodaron, methotrexate, tamoxifen, glucocorticoid, estrogen, and the other medications that affect weight within 3 months; * Patients with serious liver dysfunction (AST or/and ALT \>3 times of the upper limit of normal), or renal dysfunction (serum creatinine \>the upper limit of normal); * Patients with diseases that need control of dietary protein intake; * Patients with diseases that affect food digestion and absorption; * Patients with diagnosed diabetes or those with significantly elevated blood glucose (fasting blood glucose ≥7.0 mmol/L and/or random blood glucose ≥11.1 mmol/L); * Patients with severe cardiovascular and cerebrovascular diseases or severe hypertension (Grade 3); anemia; mental illness or memory disorder; epilepsy or antiepileptic treatment; * Patients with secondary obesity; * Patients with cancer, active tuberculosis, AIDS and other infectious diseases; * Pregnancy or lactation; * Physical disability.