Effect of Probiotics on Blood Pressure Management

Inclusion Criteria: * Eligible subjects include men and women 18 to 75 years of age with pre-hypertension who has a systemic blood between 120 and 139 mmHg and/ or a diastolic blood pressure between 80 and 80 mmHg; * Absence of any diet, dietary supplement and medications that might interfere with blood pressure and gut microbiota, especially antibiotics and probiotics. Exclusion Criteria: * Any other systemic, metabolic and cardiovascular or cerebrovascular diseases; * Type 1 diabetes, type 2 diabetes treated with insulin or other medications; * Acute illness or current evidence of acute or chronic inflammatory or infective diseases; * Participation in any diet or lifestyle program more than 2 times per week in the latest 3 months prior to recruitment; * Mental illness rendering them unable to understand the nature, scope, and possible consequences of the study.