This study, taking stable angina pectoris as a research carrier, aims to explore the preventive value of acupoint sensitization by conducting a double-blind multi-center randomized controlled trial to compare the effect of stimulating acupoints with different sensitivity on the prevention of angina pectoris. After the inclusion of eligible patients, the pressure-pain threshold of disease-related acupoints will be detected by using Von Frey detector. Then, the patients will be randomly divided into experimental group and control group. The patients in experimental group will be given acupoints pressure on the five acupoints with the lowest pressure-pain threshold, while the patients in control group will be given acupoints pressure on the five acupoints with the five acupoints with the highest pressure-pain threshold. The two groups will be treated with acupoints pressure 12 times within 4 weeks. The patients will be evaluated three times at baseline, the end of treatment and four weeks after the end of treatment respectively, including angina attack frequency, CCS classification and SAQ score.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
202
The first five acupoints in the sensitization sequence were pressed using the traditional Chinese medicine acupoint pressing technique, and each acupoint was pressed for two minutes.
The last five acupoints in the sensitization sequence were pressed using the traditional Chinese medicine acupoint pressing technique, and each acupoint was pressed for two minutes.
The West China Hospital of Sichuan university
Chengdu, Sichuan, China
Change of the number of angina attacks
Change of the number of uncomfortable events that met the criteria for angina in study period
Time frame: Change from baseline to week 8
Change of the Canadian Cardiology Society (CCS) Classification of Angina Pectoris
According to the patient's own condition scale, the patients were divided into 4 grades, the mildest being grade I and the most serious being grade IV
Time frame: Change from baseline to week 8
Change of the Seattle Angina Questionnaire(SAQ) Score
The maximum score of the scale was 100, and the higher the score, the better the quality of life and the functional state of the patients
Time frame: Change from baseline to week 8
Change of the use of Therapeutic Nitroglycerin Drugs
Change of the number of times that patients temporarily took nitroglycerin for angina attacks
Time frame: Change from baseline to week 8
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