Remineralization Potential of Pearl Powder Compared to CPP-ACP on Enamel White Spot Lesions

Cairo University62 enrolled

Overview

The aim of this study is to evaluate the remineralization potential of pearl powder on early ('white spot') lesions in enamel in orthodontic patients compared to casein phosphopeptide-amorphous calcium phosphate. The remineralisation potential will be assessed both visually and by standardised photographic image analysis. the follow up will be up to 12 months.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

White Spot Lesion

Interventions

Cpp-AcpDRUG

Remineralising agent

Pearl powderOTHER

Natural product

Eligibility

Sex: ALLMin age: 12 YearsMax age: 25 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Males or females. * Age: 12-25 years old. * Patients with good oral hygiene. * Co-operative patients who show interest to participate in the study. Exclusion Criteria: * Patients with bad oral hygiene. * Lack of patient's approval and compliance. * Presence of abnormal oral, medical, or mental condition. * Patients who are allergic to milk products. * Pregnant and lactating women.

Outcomes

Primary Outcomes

Clinical index used for visual evaluation of white spot lesions

Scores(0-No visible colour change, 1-Slight white colour change, only visible after air-drying, 2-Slight colour change with certain marked white areas, 3-White consistent colour change, 4-Distinct white colour change)

Time frame: 12 months

Secondary Outcomes

Digital photographic image analysis

Computerised software to analyse the change in the lesion

Time frame: 12 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.