The purpose of this study is to determine how interstitial lung disease can be predicted over time in early rheumatoid arthritis. The investigators will study blood and phlegm samples from participants, along with quality of life questionnaires to determine if and how the presence of ILD may impact the participants quality of life over time.
Participation involves 5 study visits over an 18 month timeframe. During each of these visits, a recent medical history and physical exam will take place, blood and phlegm will be collected, quality of life questionnaires will be administered, and a CT-scan of the chest and pulmonary function testing may be performed.
Study Type
OBSERVATIONAL
Enrollment
76
National Jewish Health
Denver, Colorado, United States
RECRUITINGChange in anti-CCP antibody test to identify the presence or development of RA in patients with or without ILD
Time frame: 18 months
Change in lung antigen targets in RA-ILD using induced sputum
Time frame: 18 months
Change from baseline for Leicester Cough questionnaire-Acute (LCQ_Acute)
Time frame: 18 months
Change from baseline for Short Form (SF_36) questionnaire
Time frame: 18 months
Change from baseline for UCSD Medical Center Pulmonary Rehabilitations Program Shortness-of-Breath questionnaire
Time frame: 18 months
Change from baseline for Multi-Dimensional Health Assessment questionnaire (MDHAQ)
Time frame: 18 months
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