Pomegranate Juice Effect on Oxidative Stress in Infertile Women During IVF Treatment

Rambam Health Care Campus40 enrolled

Overview

tTe investigators estimate pomegranate supplementation effect on oxidative stress in infertile women with PCOS, endometriosis and advanced maternal age during IVF treatment. The primary aim is to compare the obtained oxidative stress markers in follicular fluid with pomegranate supplementation vs control.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

QUADRUPLE

Enrollment

Conditions

PCOS Endometriosis Advised Maternal Age Male Factor Infertility

Interventions

Pomegranate juiceOTHER

Pomegranate juice

Apple juiceOTHER

Apple juice

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergo IVF treatment with diagnosis of PCOS/Endometriosis/MF or AMA Exclusion Criteria: * Patients who do not meet the inclusion criteria, as above

Outcomes

Primary Outcomes

Cytokines levels in follicle fluid

Cytokines (pg/mL) will be mesured by elisa.

Time frame: 2 weeks

Data from ClinicalTrials.gov

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