The primary purpose of this study is to characterize the safety, tolerability, and dose-limiting toxicities (DLTs) of relatlimab in combination with ipilimumab.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
11
Specified dose on specified days
Specified dose on specified days
Local Institution - 0023
Tucson, Arizona, United States
Number of Participants with Adverse Events (AEs)
Time frame: Up to Follow-up Period (100 days after 34 cycles [1 cycle is of 3 weeks])
Number of Participants with Serious Adverse Events (SAEs)
Time frame: Up to Follow-up Period (100 days after 34 cycles [1 cycle is of 3 weeks])
Number of Participants With Adverse Events Including Dose Limiting Toxicity
Time frame: Up to 28 days after last study drug dose (approximately up to 2 years)
Number of Participants with AEs resulting in Discontinuation
Time frame: Up to end of study (approximately 2.4 years)
Number of Participants with AEs resulting in Death
Time frame: Up to end of study (approximately 2.4 years)
Number of Participants with AEs resulting in Laboratory Abnormalities
Time frame: Up to end of study (approximately 2.4 years)
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Local Institution - 0002
Los Angeles, California, United States
Local Institution - 0005
Los Angeles, California, United States
Local Institution - 0001
Santa Monica, California, United States
Local Institution - 0015
Miami, Florida, United States
Local Institution - 0004
Chicago, Illinois, United States
Local Institution - 0003
Ann Arbor, Michigan, United States
Local Institution - 0008
Morristown, New Jersey, United States
Local Institution - 0018
Brussels, Brussels Capital, Belgium
Local Institution - 0017
Antwerp, Belgium
...and 18 more locations