The investigators intend to study the safety and effectiveness of opioid free anesthesia compared to opioid anesthesia in ambulatory surgery in children, regarding postoperative pain, hemodynamic stability, agitation and discharge times. Quality of postanesthetic care was estimated in a 24h follow up.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Enrollment
100
Patients will receive non-opioid analgesics, such as dexmedetomidine, ketamine perioperatively
Patients will receive opioid analgesics, such as fentanyl and remifentanil perioperatively
Childrens Hospital P. and A. Kyriakou Anesthesiology Department
Athens, Greece
Discharge times from the hospital
Comparison of the discharge times from the hospital between opioid free and opioid based anesthesia using Discharge criteria based on physiological scoring system, evaluating respiration, circulation, level of consciousness, postoperative pain, postoperative nausea and vomiting and surgical site. A score 12 or more allows patient to leave safely from the hospital.
Time frame: 4 hours
Severity of postoperative pain
Comparison of the severity of postoperative pain between opioid free and opioid based anesthesia using Visual Analogue Scale for children aged 7 years and more. We instruct the patient to point to the position on the line between the faces to indicate how much pain they are currently feeling. The far left end indicates "no pain"(0) and the far right end indicates "worst pain ever."(10)
Time frame: 24 hours
Severity of postoperative pain
Comparison of the severity of postoperative pain between opioid free and opioid based anesthesia using the Face, Legs, Activity, Cry, Consolability scale or FLACC scale for children between the ages of 3 years and 7 years. The scale has five criteria, which are each assigned a score of 0, 1 or 2.The scale is scored in a range of 0-10 with 0 representing no pain.
Time frame: 24 hours
Extubation time
Comparison of extubation time, time interval between discontinuation of anesthetics and extubation between the two groups
Time frame: 30 minutes
Discharge time from PACU
Comparison of discharge time from postanesthesia unit, time interval between arrival from operating room until leaving postanesthesia unit, between the two groups using Aldrete scale, score of 9 or greater allows patient to leave postanesthesia unit
Time frame: 60 minutes
Cost effect
Comparison of hospitalization fees among the two groups
Time frame: 24 hours
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