The MICROSPA project aims to compare gut microbiota, serum cytokines, and PBMC of patients suffering from Crohn's disease (CD) associated or not to spondylarthritis (SpA). 3 groups of patients will be analyzed: patients suffering from CD alone, patients suffering from SpA alone, patients suffering from CD and SpA. One group of healthy controls will be analysed as a comparator. Fecal microbiota will be determined by bacteriome, virome and fungome NGS sequencing
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SCREENING
Masking
NONE
Enrollment
240
virome, bacteriome, fungome NGS sequencing
Central Hospital
Nancy, Lorraine, France
RECRUITINGSaint Antoine Hospital
Paris, France
RECRUITINGAlpha and Beta diversity of Fecal bacteriome
Alpha (number of species) and Beta diversity (distribution of species)
Time frame: + 6 months
Alpha and Beta diversity of Fecal fungome
Alpha (number of species) and Beta diversity (distribution of species)
Time frame: + 6 months
Alpha and Beta diversity of Fecal virome
Alpha (number of species) and Beta diversity (distribution of species)
Time frame: + 6 months
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