Improved understanding of the long-time healthcare utilisation of childhood cancer survivors is relevant as it can be seen as a proxy for the population's morbidity. The investigators will conduct a historic population-based matched cohort study using Danish nationwide registry data. Eligible children are children 1.0-17.9 years diagnosed with Acute lymphoblastic leukaemia (ALL) in Denmark from 1994 till 2016. The primary outcome is yearly contact rates to primary healthcare.
Acute lymphoblastic leukaemia (ALL) is the most frequent single form of cancer in children accounting for 40-45 new cases every year in Denmark. Over the past decades, advances in treatment have led to an increasing number of children who survive cancer and more than 80% of children with ALL now become long-term survivors. This means a growing population of childhood ALL survivors. In survivors, the cancer itself and treatment late-effects can lead to ongoing health care use. Register studies of long-term survivors of childhood cancer have shown an increased risk of hospitalisation compared to the general population. It is mentioned in many of the studies that contact rates could be underestimated when looking at hospital contacts only. The literature about non-hospital-based contacts with a doctor in childhood cancer survivors is scarce.
Study Type
OBSERVATIONAL
Enrollment
7,348
The cohort of ALL survivors has all been diagnosed and treated for ALL in childhood
Department of Public Health
Aarhus C, Denmark
The yearly contact rate to general practice for ALL survivors and controls
Analysing longitudinal health care data with analysis of both first and recurrent events
Time frame: 1-20 years follow-up
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