Characterize Tumor Hypoxia by Magnetic Resonance Imaging

Inclusion Criteria: * The minimum age for this study is men 40 years and older. Prostate cancer mainly affects men over the age of 40. * Patients with Caucasian and African American race * Patients with pathology-proven prostate cancer (Gleason 6 or higher) * Patients who have not yet undergone therapy (systemic drugs, radiation, or prostatectomy) * Patients who will have a radical prostatectomy as standard of care. * Ability to understand and the willingness to sign an IRB-approved informed consent document (either directly or via a legally authorized representative). Exclusion Criteria: * Patients who have already received some form of treatment or are not planning to undergo radical prostatectomy for treatment. * Patients with any other cancer along with prostate cancer. * Uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.