Pain control modalities were evaluated after thyroidectomy.
Pain control modalities were evaluated after thyroidectomy. Patients were randomized to one of two pain control regimens. The control group received conventional opioid based post operative analgesia while the test group received an enhanced recovery after surgery (ERAS) based anesthesia with use of acetaminophen and non-steroidal anti-inflammatory drugs for the post operative period with opioid medications available for break through pain only. Pain scores (measured on visual analog scale) and opioid use (measured in morphine equivalent dose) were measured after completion of the operation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Patients receive acetaminophen 650mg every 4 for pain level 1-3, hydrocodone/acetaminophen 5/325mg every 4 for pain level 4-6, or hydrocodone/acetaminophen 10/650mg every 4 for pain level 7-10 on as needed basis.
Patients receive standing dose of acetaminophen 650mg every 8 hours and ibuprofen 800mg every 8 hours with alternating ibuprofen and acetaminophen every 4 hours.
MedStar Washington Hospital Center
Washington D.C., District of Columbia, United States
visual analog scale pain level
Pain level from 0 (no pain) to 10 (worst pain imaginable).
Time frame: 1 hour post operatively
visual analog scale pain level
Pain level from 0 (no pain) to 10 (worst pain imaginable).
Time frame: 6 hour post operatively
visual analog scale pain level
Pain level from 0 (no pain) to 10 (worst pain imaginable).
Time frame: 24 hour post operatively
visual analog scale pain level
Pain level from 0 (no pain) to 10 (worst pain imaginable).
Time frame: 7 days post operatively
opioid use
the dose of opioid received by the patient
Time frame: with the first 24 hours post operatively
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