The purpose of this study is to evaluate the safety and preliminary efficacy of CC-92480 in combination with standard treatments.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
424
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Recommended Dose
Time frame: Up to approximately 3 years
Recommended regimen as measured by dose-limiting toxicities
Time frame: Up to approximately 3 years
Number of participants with Adverse Events (AEs)
Time frame: From first participant first visit until 28 days after the last subject discontinues study treatment, up to 5 years
Overall response rate (ORR)
Time frame: Up to approximately 5 years
Time-to-response (TTR)
Time frame: Up to approximately 5 years
Duration of response (DOR)
Time frame: Up to approximately 5 years
Complete Response (CR) rate
Time frame: Up to approximately 5 years
Very good partial response (VGPR) rate - Cohorts D and E
Time frame: Up to approximately 5 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Local Institution - 119
Denver, Colorado, United States
Local Institution - 104
Tampa, Florida, United States
Local Institution - 108
Atlanta, Georgia, United States
Local Institution - 112
Chicago, Illinois, United States
Local Institution - 107
Chicago, Illinois, United States
Local Institution - 117
Boston, Massachusetts, United States
Local Institution - 101
Boston, Massachusetts, United States
Local Institution - 118
Boston, Massachusetts, United States
Local Institution - 113
Detroit, Michigan, United States
Local Institution - 106
Rochester, Minnesota, United States
...and 39 more locations