Impact of Embryo Cryopreservation on Birth Weight

University Hospital, Montpellier183 enrolled

Overview

Birth weight (BW) is higher after frozen embryo transfer (FET) than after fresh embryo replacement. No study has compared the BW of siblings conceived using the same oocyte/embryo cohort. The aim of this study was to determine whether the freezing-thawing procedure is involved in such difference.

Study Type

OBSERVATIONAL

Enrollment

183

Conditions

Infertility

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 43 Years

Medical Language ↔ Plain English

Inclusion Criteria: * sibling pairs where fresh embryo replacement resulting in a singleton live birth was followed by transfer of one or two frozen embryos from the same cohort that resulted in a singleton live birth, between May 2007 and June 2015. Exclusion Criteria: * Twin pregnancies and stillbirths were excluded. If the BW of at least one sibling was unknown, the pair was not included in the study.

Locations (1)

Uh Montpellier

Montpellier, France

Outcomes

Primary Outcomes

birthweight

change after FET than after fresh embryo transfer

Time frame: 1 day

Data from ClinicalTrials.gov

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