Effect of Vitamin D on the Size of Fibroids in Women With Vitamin D Deficiency

Fundación IVI15 enrolled

Overview

Vitamin D supplementation in patients with uterine fibroids who present hypovitaminosis D to re-establish their normal serum values could stabilize the size of the uterine fibroids and thus prevent their growth or reduce their size thanks to the anti-proliferative action of Vitamin D on the myoma cells.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Size of the Uterine Fibroids

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed with at least one fibroid \> 3 cm * With hypovitaminosis D (25(OH)D \< 30 ng/ml) * BMI \< 30 * No hormonal treatment in the 3 months prior to the ultrasound study Exclusion Criteria: * Black race * Symptomatic fibroids subsidiary to hormonal or surgical treatment * Desire of gestation in the next 6 months * Presence of degenerating adenomyosis or fibroids * Treatment with sexual hormones: mifepristone, aGnRH or any other medication that may interfere with fibroids. * History of neoplasia of gynecological origin and/or existence of uterine malformations. * Hypercalcemia or abnormal liver or kidney function is present

Locations (1)

Fundacion IVI

Valencia, Spain

Outcomes

Primary Outcomes

volume of the uterine fibroids

Time frame: 3 months

Data from ClinicalTrials.gov

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