The objective of this clinical study is to evaluate the efficacy and safety by comparing the BR1010 treatment group to the fimasartan/amlodipine treatment group at Week 8 in patients with essential hypertension who do not adequately respond to Fimasartan/Amlodipine combination
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
257
Active Comparator: a fixed dose combination of Fimasartan/Amlodipine or placebo
Boryung Pharmaceutical Co., Ltd
Seoul, South Korea
sitting systolic blood pressure
The change of sitting systolic blood pressure
Time frame: 8weeks from Baseline Visit
sitting systolic blood pressure
The change of sitting systolic blood pressure
Time frame: 2weeks and 4weeks from Baseline Visit
sitting systolic blood pressure and sitting diastolic blood pressure
The change of sitting systolic blood pressure and sitting diastolic blood pressure
Time frame: 2weeks, 4weeks and 8weeks from Baseline Visit
The ratio of subjects who get normalized blood pressure
The ratio of subjects who get normalized blood pressure
Time frame: 2weeks, 4weeks and 8weeks from Baseline Visit
Response Rate
Response Rate
Time frame: 2weeks, 4weeks and 8weeks from Baseline Visit
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