Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Postoperative Pain Following Bunionectomy

Inclusion Criteria: * Men and women must be between the ages of 18 to 70 years, inclusive. Female subjects must meet additional criteria in relation to childbearing potential. * Subjects must be undergoing a planned bunionectomy without collateral procedures. * Subjects must have the ability to provide written informed consent. * Subjects must have the ability to understand study procedures and communicate clearly with the Investigator and staff. * Subjects must be classified as American Society of Anesthesiologists risk class I to II. Exclusion Criteria: * Subjects undergoing emergency or unplanned surgery. * Subjects undergoing a repeat operation. * Subjects with pre-existing conditions (other than bunion) causing preoperative pain at the site of surgery. * Female subjects who are pregnant or breastfeeding. * Diagnosis of chronic pain and ongoing or frequent use of pain medications.