Recruit of healthy, precancer and colorectal cancer patients and record necessary information of demographic and also other messages. All the volunteers were asked to provide samples including stool, blood, urine and tissues. This protocol is performed with the permission of the ethics committee and all the participants were provided with informed consent.
Healthy subjects, precancer patients identified by colonoscopy or colonoscopy history and colorectal cancer patients identified by two independent pathologists will be enrolled. The demographic message including age, weight, height, drug history, family history of all participants will be recorded. Blood, stool and urine samples will be collected of all subjects. Tumor and adjacent tissue samples of colorectal cancer and precancer patients were collected, as well as normal tissue of healthy subjects.
Study Type
OBSERVATIONAL
Enrollment
2,000
Shanghai 10th People's Hospital
Shanghai, Shanghai Municipality, China
RECRUITINGGut microbiota structure and function difference between colorectal cancer, precancer and healthy controls
The results were based on the 16S rRNA metagenomic sequencing.
Time frame: average of 5 years
Metabolic difference of blood samples between colorectal cancer, precancer and healthy controls
The metabolites of the blood samples by LC-MS will be detected.
Time frame: average of 5 years
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