Carotid Atherosclerosis in Patients With Aortic Coarctation

Skane University Hospital116 enrolled

Overview

Despite aortic coarctation (CoA) repair these patients have cardiovascular complications and coronary artery disease is the most common cause of death.

The aim with this study was to measure intima-media thickness (IMT) and plaques in arteries compared to cardiovascular markers in controls and patients with CoA.

Study Type

OBSERVATIONAL

Enrollment

116

Conditions

Atherosclerosis Aortic Coarctation

Interventions

Ultrasound measurementOTHER

Ultrasound measurement

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * sex and age-matched controls Exclusion Criteria: * acute and chronic inflammation disease, underlying malignancies and diabetes mellitus.

Outcomes

Primary Outcomes

Intima-media thickness

Measurement in mm

Time frame: Intima-media thickness will be measured at one time point namely at inclusion. Data will be reported when study is completed, an average of 2 year.

Secondary Outcomes

Cardiovascular markers

A multiplex platform to analyze circulating blood levels biomarkers was used.

Time frame: Blood samples will be taken at one time point namely at inclusion. Then biomarkers will be analysed when study is completed. Data will be reported when study is completed, an average of 2 year.

Data from ClinicalTrials.gov

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