This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.
Study Type
OBSERVATIONAL
Enrollment
6,000
data generated by medical review include Medical history, Medications at presentation, during hospitalization and at discharge, New York Heart Association (NYHA) class, Killip class, Electrocardiographic (ECG) data, echocardiographic data, Interventions (Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft (CABG), Implantable Cardioverter Defibrillator (ICD) implantation, Cardiac Resynchronization Therapy (CRT) Implantation), Outcome Information: all-cause death, HF hospitalizations
data generated by direct IT export include Anthropometric data (age, sex, height, weight), Vital signs, Laboratory data
Cardiology, University Hospital Basel
Basel, Switzerland
RECRUITINGnumber of all-cause death
number of all-cause death in patients hospitalized with ACS and AHF during the years 2010-2023.
Time frame: 1 to 8 years after hospitalization
number of HF hospitalizations
number of new HF hospitalizations in patients hospitalized with ACS and AHF during the years 2010-2023
Time frame: 1 to 8 years after hospitalization
number of cardiovascular death
number of cardiovascular death in patients hospitalized with ACS and AHF
Time frame: 1 to 8 years after hospitalization
number of cardiovascular hospitalizations
number of cardiovascular hospitalizations
Time frame: 1 to 8 years after hospitalization
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