Laser pulsed energy will be delivered over an optical fiber to create channels into damaged cartilage of the knee or knees. The channels have a diameter of approximately 100 microns or less and an approximate depth of 1 millimeter or less. Bone marrow aspirate will then be delivered into the damaged joint.
The creation of micro-channels into damaged knee cartilage will facilitate the movement of fluid into and out of the tissue to allow for more efficient nutrient diffusion. The addition of bone marrow aspirate will provide additional growth factor enriched nutrition to the tissue. The goal of this combination therapy is to facilitates the body's own reparative processes leading to improved patient well being.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
45
Bone marrow aspirate combined with laser to alter the cartilage matrix to facilitate repair
Trinity Sports Medicine
Steubenville, Ohio, United States
MRI
Pre procedure MRI and post MRI is taken to measure disease modification
Time frame: one year
VAS Score
Pre procedure and post procedure Pain score
Time frame: one year
KOOS score
Pre procedure and post procedure Improvement in daily living and pain
Time frame: one year
Treadmill Test
Pre procedure and post procedure, the patient will walk for 12 minutes with a gradual increase and a change in pain will be evaluated
Time frame: one year
Swiss Ball wall squat test
Swiss Ball wall squat test to asses functional recovery.
Time frame: one year
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