Evaluation of an Arterial Calcification Score as a Predictive Factor of Anastomotic Leakage in Right Colectomy

Centre Hospitalier Departemental Vendee615 enrolled

Overview

Anastomotic leakage is the major postoperative complication in right colectomy. Evaluation of calcification on coeliac trunk and mesenteric arteries on the preoperative CT scan could allow the identification of patient at-risk of postoperative complications. A monocentric retrospective study performed at CHD Vendée concluded than a calcification score over or equal to 3 was associated with a higher risk of developping an anastomotic leakage. The aim of this prospective multicentric study is to validate a calcification score based on preoperative CT scan analysis and focussing at coeliac trunk and mesenteric arteries.This study will involve patients operated on with a scheduled right colectomy.

Study Type

OBSERVATIONAL

Enrollment

615

Conditions

Right Colectomy

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years old * Scheduled right colectomy with restoration of digestive continuity * Patient who has had or will have a preoperative abdominal-pelvic CT scan with or without contrast injection * Patient with the ability to understand the protocol and agree to participate in the study. * Affiliated with a social security system Exclusion Criteria: * Patient requiring a right colectomy or ileocaecal resection for chronic inflammatory bowel disease or on long-term corticosteroid therapy * Patient with a history of colic resection * Patient under guardianship, curatorship, or deprived of liberty * Pregnant, postpartum or breastfeeding women * Minor patients

Locations (12)

CHU Angers

Angers, France

Hopital privé de Sévigné

Cesson-Sévigné, France

CH de Challans

Challans, France

CH de Cholet 1 rue Marengo

Cholet, France

Centre Hospitalier de Fougères

Fougères, France

CHD Vendée

La Roche-sur-Yon, France

Centre Hospitalier du Mans

Le Mans, France

Clinique Mutualiste de la Porte de l'Orient

Lorient, France

CHU de Nantes

Nantes, France

Centre Hospitalier de Saint Brieuc

Saint-Brieuc, France

...and 2 more locations

Outcomes

Primary Outcomes

Total calcification score associated with the occurrence of anastomotic leakage

Sum of the calcification scores of the following 4 segments (≥3) associated with the occurrence of anastomotic leakage within 6 weeks postoperatively. 4 segments: * Ostium of celiac artery * Ostium of superior mesenteric artery * first segment of superior mesenteric artery * distal segment of superior mesenteric artery Each segment will be assigned a score between 0 and 2. Total score range : 0-8

Time frame: 6 weeks after surgery

Secondary Outcomes

Calcification score of each segment associated with the occurrence of anastomotic leakage

4 segments: * Ostium of celiac artery * Ostium of superior mesenteric artery * first segment of superior mesenteric artery * distal segment of superior mesenteric artery Each segment will be assigned a score between 0 and 2.

Time frame: 6 weeks after surgery

Morbidities defined according to Clavien-Dindo classification

Morbidities defined according to Clavien-Dindo classification occurring at 6 weeks postoperatively

Time frame: 6 weeks after surgery