The combined effect of omega-3 fatty acid and vitamin D3 on lipid profile levels and oxidized low density lipoprotein: a randomized controlled trial in males and females with vitamin D deficiency
Nothing is published in the literature about the combined effect of vitamin D3 (VD3) and omega-3 fatty acids (omega-3FA) on on lipid profile levels and oxidized low density lipoprotein This study will be conducted to investigate effect of VD3 and omega-3FA alone and with each other on lipid profile levels and oxidized low density lipoprotein in Jordanian people with vitamin D deficiency. This randomized, controlled clinical trial will be designed to test effects of 50,000 IU VD3 weekly and 300 mg omega-3FA daily for eight weeks, separately and with each other, on on lipid profile levels and oxidized low density lipoprotein
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
111
VD3 50000 IU/ week for 8 weeks
Omega 3 FA group 300 mg once daily for 8 weeks
50000 IU VD3/week for 8 weeks and 300 mg of omega- 3 FA once daily for 8 weeks
Applied Science University
Amman, Jordan
VD 3
Serum level of 25-hydroxyvitamin D
Time frame: 8 weeks
Total Cholesterol
serum level of total cholesterol
Time frame: 8 weeks
HDL Cholesterol
serum level of HDL Cholesterol
Time frame: 8 weeks
LDL Cholesterol
serum level of LDL Cholesterol
Time frame: 8 weeks
triglycerides
serum level of triglycerides
Time frame: 8 weeks
oxidized LDL
serum level of oxidized LDL
Time frame: 8 weeks
PTH
serum level of PTH
Time frame: 8 weeks
Calcium and Phosphorus
serum level of Calcium and Phosphorus
Time frame: 8 weeks
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no intervention is given