Ecopipam Tablets to Study Tourette's Syndrome in Children and Adolescents

Inclusion Criteria: * ≥ 6 and \< 18 years of age * ≥ 18 kg (\~ 40 lbs.) * TS diagnosis and both motor and vocal tics that cause impairment with normal routines * Minimum score of 20 on the YGTSS-Total Tic Score * May not be taking any medications used to treat motor or vocal tics for at least 14 days prior to Baseline. * Effective contraception during the study and 30 days after last study dose for sexually active subjects Exclusion Criteria: * Certain mood or psychiatric disorders (i.e., dementia, bipolar disorder, schizophrenia, major depressive disorder) * Unstable medical illness or clinically significant lab abnormalities * Risk of suicide * Pregnant or lactating women * Moderate to severe renal insufficiency * Hepatic insufficiency * Positive urine drug screen * Unstable doses for drugs to treat anxiety, depression, Attention Deficit Hyperactivity Disorder * Certain medications that would lead to drug interactions * Recent behavioral therapy