Amyotrophic lateral sclerosis (ALS) is a kind of motor neuron degeneration disorder without effective therapy. This registered cohort study will provide further insights into the clinical course of ALS, and investigate disease-relative risk factors and the genetic background of Chinese ALS patients.
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease (MND), which is characterized with highly clinical heterogeneity and no effective treatment is available now. The purpose of this registered cohort is to observe the natural history of ALS patients in China, and then identify some factors correlated with disease progression. Besides, ALS-related gene mutations will be screened and explore novel disease causing gene as well.
Study Type
OBSERVATIONAL
Enrollment
2,000
Department of Neurology, First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, China
RECRUITINGAge at death
the time when patient die
Time frame: 10 years
Age of endotracheal intubation or tracheotomy
the time for the patient accepted endotracheal intubation or tracheotomy
Time frame: 10 years
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