ATtention Test and Executive Functions After STroke to Predict Depression.

Centre Hospitalier St Anne74 enrolled

Overview

The purpose of this study is to determine whether cognitive function evaluation (sustained attention, executive functions, working memory) during acute post-stroke is predictive of a 3 months post-stroke depression.

1. Baseline visit: after neurologic stability, 14 days or less after stroke and before discharge. 2. First assessment : 1. Neurologic data: morphologic data (MRI of the brain), stroke severity (NIHSScore), aphasia assessment (Boston Diagnostic Aphasia Examination) if NIHS verbal score ≥1, hemineglect assessment (Bells test). 2. Personal data assessment : i. Socio demographic : age, gender, marital status, employment, level of education ii. Medical history: medical treatments, psychiatric and non psychiatric history. c. Psychiatric assessment i. Mini International Neuropsychiatric Interview - depression ii. Beck Depression Inventory iii. Clinical Global Impression iv. Standardized Assessment of Personality - Abbreviated Scale (SAPAS) v. Fageström-C vi. Alcohol Use Disorders Identification Test (AUDIT-C) d. Cognitive assessment: i. Verbal memory : Dubois's five words ii. Clock drawing test iii. D2test (computerized) iv. Verbal fluency (Cardebat) v. Working memory (digit span WAIS 3) vi. Brixton (computerized) 3. Assessment 3 months after the first assessment. Phone call and psychiatric assessment: MINI depression, Beck Depression Inventory. Barthel index and Quality of Life assessment.

Study Type

INTERVENTIONAL

Allocation

Purpose

SCREENING

Masking

NONE

Enrollment

Conditions

Post-stroke Depression

Interventions

Thymic historyOTHER

This interview concerns mainly the nature of the previous psychiatric and psychological care

Evaluation of the psychiatric disordersOTHER

Mini International Neuropsychiatric Interview for the positive diagnosis of depression - under the MINI score of depression.

Cognitive evaluationOTHER

They will be held consecutively to the patient's bedside interview on the same day. Some tests will be computerized, others will be in paper form.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 or more * Ischemic or hemorragic stroke, diagnosed with radiology : cerebral CT or MRI, 14 days or less after stroke * Signed Consent * Social insurance regime affiliation Exclusion Criteria: * Death * No possibility of follow-up * No French-speaker : insufficient command of French * Deprivation of liberty : judicial or administrative decision * D2 test assessment impossibility * Aphasia with major disorder of the understanding (Boston \<8) * Antidepressant treatment during stroke * Depression during stroke * protected people

Locations (1)

Neurology service

Paris, France

Outcomes

Primary Outcomes

Post stroke depression

Whether or not a post-stroke depression occurs. occurrence of post-stroke depression assessed with Mini International Neuropsychiatric Interview (MINI), subscale depression .

Time frame: 3 months

Secondary Outcomes

Post-stroke depression population characterization

Age, gender, marital status, occupation, level of education, laterality of stroke,and medical and psychiatric history will be collected during the inclusion interview and cognitive tests

Time frame: 1 day

Data from ClinicalTrials.gov

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