A Feasibility Study of a Novel Phototherapy System for the Management of Acute Burns

Inclusion Criteria: * Males or females age \> 18 to \< 65 * BMI \> 20 kg/m2 * Patients anticipated to receive inpatient care for a minimum of 72 hours at the respective medical facility for partial thickness second-degree, deep partial thickness second-degree and/or full thickness third-degree burn wounds. * Patients who have a \> 5% to \< 50% Total Body Surface Area (TBSA) wound. * Patients are willing and able to adhere to the therapy and protocol. * Female of childbearing potential must be willing to use acceptable methods of contraception. * Patients may or may not have clinical signs and symptoms of burn site infection at baseline. * Subject has read, understood and signed the approved ICF before screening procedures either by the patient or their legally authorized representative. Exclusion Criteria: * Subjects with burns \> third-degree (i.e. involvement of deeper tissues, such as muscle, tendons, or bone) * Patients deemed not medically stable by the treating Investigator. * Patients with burn wounds limited to their head or genitalia. * Patients currently enrolled or participating in another investigational device, drug or biological trial that would interfere with the Lumina24TM application. * Patients with inhalation burns. * Patients who are clinically septic. * Patients are pregnant. * Patients on a ventilator, who are undergoing acute fluid resuscitation, are hemodynamically unstable or are deemed 'comfort measures only'. * In the opinion of treating physician, patient not expected to survive beyond 30 days. * Pregnant or lactating status. Pregnancy as determined by a positive pregnancy test at screening or baseline. * Known history of HIV infection, or active Hepatitis B or Hepatitis C infection. * Cancer requiring chemotherapy or radiation within previous 6 months or resection within the last 5 years (other than basal cell carcinoma. * Known chronic renal failure (serum creatine \> 2 mg/dL) or chronic liver disease. * Pre-existing medical condition requiring current use of immunosuppressive medication or systemic steroids * Pre-existing medical conditions that would interfere with wound healing (i.e. diabetic patients with Hemoglobin A1c test result \> 8%, malignancy, autoimmune disease) * Subjects with psychiatric conditions that are anticipated to result in protocol noncompliance * Chronic illicit drug or alcohol abuse that is anticipated to interfere with patient compliance with the protocol * Subject is incarcerated at the time of screening.