Relationship Between Cardiopulmonary Exercise Testing and Ca-P in Chronic Kidney Disease (CKD)

Shahid Beheshti University of Medical Sciences200 enrolled

Overview

Reductions in exercise capacity associated with exercise intolerance augment cardiovascular disease risk and predict mortality in chronic kidney disease. This study utilized cardiopulmonary exercise testing to (a) investigate mechanisms of exercise intolerance; (b) unmask subclinical ca and p and vitamin D abnormalities that may precede cardiovascular disease in chronic kidney disease.

Cardiopulmonary exercise testing will carry out in Stage 3-5 chronic kidney disease patients ; estimated glomerular filtration rate \<60 ml/min/1.73 m2) and biochemistry will be added (Ca P Via D PTH FGF23).

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Ckd-Mbd

Interventions

CPETDIAGNOSTIC_TEST

CPET

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * CKD Patients with GFR \<60 non-dialysis * age\<18 Exclusion Criteria: * HTN * not signing consent * active coronary disease

Locations (1)

Nooshin Dalili

Tehran, Iran

Outcomes

Primary Outcomes

Calcium x phosphorus change in stage 3-5

CaxP change

Time frame: 12 MONTHS

CPET score change

Evaluation of CPET score change

Time frame: 12 MONTHS

Secondary Outcomes

Renal Function change

GFR change

Time frame: 12 MONTHS

Data from ClinicalTrials.gov

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