In addition to intraocular pressure blood perfusion pressure in the optic nerve is an important factor determing the cause of glaucoma. Increasing evidence suggests that in glaucoma patients retinal blood may be decreased.
According to the World Health Organization (WHO) glaucoma is the second leading cause of blindness. Glaucoma is a global problem, which is becoming even more important as the human life expectancy increases. Although the causes of glaucoma are uncertain, mainly intraocular pression (IOP), genetics, and ocular blood perfusion pressure in the optic nerve determine the cause of the disease. Increasing evidence suggests that in glaucoma patients retinal blood flow is decreased leading to progression and to damage of the optic nerve. In order to measure the peripapillary blood flow a variety of devices using different techniques of flowmetry have been developed. In this study, the reproducibility of the retinal flowmetry measured with the LSFG-NAVI device from Nidek will be investigated. A high reproducibility is crucial for the clinical value of any measuring device.
Study Type
OBSERVATIONAL
Enrollment
44
Non-invasive, real-time imaging and measurement of ocular blood flow of the optic disc and peripapillary region
Department of Ophthalmology
Zurich, Canton of Zurich, Switzerland
Coefficients of variation (COV)
COVs from 3 measurements of ocular blood flow at visit 1 of observer 1 and at visit 1 of observer 1 and from observer 2 will be computed.
Time frame: 1 month
intraclass correlation coefficients (ICCs)
Intraobserver ICC, interobserver ICC, and inter-session ICC will be computed
Time frame: 1 month
Cofounder
Blood pressure will be checked as potential cofounder
Time frame: 1 month
Cofounder
heart rate will be checked as potential cofounder
Time frame: 1 month
Cofounder
spherical equivalent will be checked as potential cofounder
Time frame: 1 month
Cofounder
intraocular pressure will be checked as potential cofounder
Time frame: 1 month
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