Management of Signs and Symptoms Associated With Dry Eye Disease

Inclusion Criteria: * Subjects with moderate dry eye defined as corneal fluorescein staining score of ≥ 3 * Age ≥ 18 years * Distance best corrected visual acuity better than 20/60 Snellen equivalent in each eye * Willing to sign a written informed consent to participate * Able to follow study instructions, with the intention of completing all required visits Exclusion Criteria: * Presence of persistent corneal epithelial defect or ulcer in either eye * Presence of active ocular infection in either eye * Presence of ocular inflammation that is not related to keratoconjunctivitis sicca, e.g., allergy, severe blepharitis * Presence of other corneal disorder(s) that give rise to reduced corneal sensitivity, such as recurrent herpes keratitis * Presence of corneal diseases other than dry eye that can disturb the pre-corneal tear film such as epithelial basement membrane dystrophy (EBMD) * Contact lens wear * History of recent ocular surgery/trauma, which could affect corneal sensitivity, e.g., corneal transplantation, LASIK * Presence of cicatricial ocular surface diseases * A medical or ocular condition, or a personal situation, which in the principal investigator's opinion, is not appropriate for participation in the trial * Any scheduled or planned ocular or systemic surgery or procedure during the study * Pregnancy and women who are expecting to be pregnant. * Current enrolment in another interventional drug or device study or participation in such a study within 30 days of anticipated entry into this study