Percutaneous vertebroplasty has been applied widely to treat bone metastases. The injected cement may strengthen the affected bone to prevent pathological fractures and relieve the pain. Moreover, the thermal reaction (70°C) due to polymerisation of cement also contributes to tumour destruction. The cement dose and diffusion pattern may be significant factors for the treatment efficacy, which can be affected by the inner pressure of the metastases. The investigators will apply a rotary cutter to destroy the structure of metastases to alleviate the pressure in the metastases. Then, more cement will be injected, which may effectively interdigitates with the surrounding bone and generate more thermo to kill the tumor cells.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
70
The cement is injected into the bone metastases directly.
The rotary cutter is applied before the cement injection. Then, the cement is injected with lower pressure.
960 Hospital of PLA
Jinan, Shandong, China
RECRUITINGBack pain: Visual analogue scales system
Measuring and comparing the pre- and post-operative back pain via Visual analogue scales (VAS) system with values from 0 to 10 (0 indicating no pain and 10 indicating the worst pain). Patients with a VAS score lower than 3 were classified as the effective group.
Time frame: 3 months
The patterns of cement opacification
The patterns of cement opacification were classified as solid patterns (cement forms a mass), trabecular patterns (cement spread along the fine bone trabeculae), and mixed patterns (cement forms a mass with spreading along the fine bone trabeculae).
Time frame: during the procedure of vertebroplasty
Cement leakage
The presence or absence of cement leakage is assessed in the groups with and without rotary cutter.
Time frame: during the procedure of vertebroplasty
Cement volume
The injected cement volume were evaluated in the two groups.
Time frame: during the procedure of vertebroplasty
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