A double-blind crossover randomized controlled trial to investigate the effects of the AVACEN device on postprandial blood glucose. The AVACEN device creates negative pressure around the hand while heating the palm. Two sham devices, one providing heat but no vacuum and one providing neither heat nor vacuum were also used. Each subject will use each of these three devices during the first hour of a 2-hour oral glucose tolerance test on separate visits. Subjects arrived in the morning following an overnight fast. Fasting blood glucose, blood pressure, tympanic temperature, and subjective thermal ratings were measured before and throughout the 2-hour oral glucose tolerance test.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
13
The AVACEN 100 pulls a -30mmHg vacuum around the hand from the wrist down and applies heat (108 Fahrenheit) to the palm
The AVACEN 100 applies heat (108 Fahrenheit) to the palm
The AVACEN 100 does not provide heat or vacuum
Jeff Moore
San Diego, California, United States
Postprandial Blood Glucose
Measuring peak postprandial blood glucose with Contour Next glucometer
Time frame: 30 minutes
Blood Pressure
Measuring blood pressure with automated cuff
Time frame: 30 minutes
Tympanic Temperature
Measuring tympanic temperature with infrared thermometer
Time frame: 30 minutes
ASHRAE 7 point thermal sensation scale
Measuring subjective temperature with thermal sensation scale
Time frame: 30 minutes
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