The influence of thyroid autoantibodies on thyroid function in pregnancy after fertility treatment is not well known. The objectives of the present study are: 1. To monitor the course of thyroid function during pregnancy and to compare between women with and without thyroid autoantibodies. 2. Compare pregnancy outcome between women with and without thyroid antibodies
Thyroid autoantibodies and / or abnormal thyroid function are associated with fertility problems. A possible explanation for this is, an influence of thyroid autoantibodies on the functioning of the thyroid gland. It is therefore recommended to check thyroid gland function and for the presence of autoantibodies before pregnancy. In general, 2 types of thyroid autoantibodies are known: anti-thyreoperoxidase autoantibodies and anti-thyroglobulin autoantibodies. In case of abnormal thyroid function, treatment is sometimes necessary in regards to fertility. The risk of abnormal thyroid function is increased in women with thyroid autoantibodies during pregnancy. Therefore, thyroid function is regularly monitored during pregnancy in women with thyroid antibodies. The influence of thyroid autoantibodies on thyroid function in pregnancy after fertility treatment is not well known. The objectives of the present study are: 1. To monitor the course of thyroid function during pregnancy and to compare between women with and without thyroid autoantibodies. 2. Compare pregnancy outcome between women with and without thyroid antibodies
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
900
blood test for thyroid antibodies and thyroid function (TSH, FT4)
questionnaire for treatment outcome: pregnancy, no pregnancy, miscarriage, delivery
UZ Brussel
Brussels, Belgium
RECRUITINGthyroid fonction
TSH, FT4 evolution during pregnancy
Time frame: 12 months
cumulative delivery rate
live birth delivery after IVF stimulation
Time frame: 12 months
cumulative pregnancy rate
pregnancy rate after IVF stimulation
Time frame: 12 months
miscarriage rate
miscarriage rate after IVF stimulation
Time frame: 12 months
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